Swine flu outbreak spreads to Asia, Middle East


Tamiflu, the generic name for the antiviral drug oseltamivir, seems to be effective against the new strain.

Swine flu outbreak spreads to Asia, Middle East
Cases confirmed in New Zealand, Israel after officials raise alert level


Swine flu worries world
http://www.msnbc.msn.com/id/30410284/displaymode/1247/

msnbc.com staff and news service reports
updated 8:06 a.m. ET April 28, 2009
The swine flu outbreak crossed new borders Tuesday with the first cases confirmed in the Middle East and the Asia-Pacific region, as the number of deaths in Mexico blamed on the virus surpassed 150.
With the swine flu having already spread to at least six other countries besides Mexico, authorities around the globe are like firefighters battling a blaze without knowing how far it extends.
"At this time, containment is not a feasible option," said Keiji Fukuda, assistant director-general of the World Health Organization, which raised its alert level on Monday
New Zealand reported Tuesday that 11 people who recently returned from Mexico contracted the virus. Tests conducted at a World Health Organization laboratory in Australia had confirmed three cases of swine flu among 11 members of the group who were showing symptoms, New Zealand Health Minister Tony Ryall said.
'Mild illness'Those infected had suffered only "mild illness" and were expected to recover, Public Health Director Mark Jacobs said. There are 43 more suspected cases in the country, officials said.
The Israeli Health Ministry on Tuesday confirmed the region's first case of swine flu in the city of Netanya. The 26-year-old patient recently returned from Mexico and had contracted the same strain, Health Ministry spokeswoman Einav Shimron.
Meanwhile, a second case was confirmed Tuesday in Spain, Health Minister Trinidad Jimenez said, a day after the country reported its first case.
The number of U.S. cases doubled to 50 early Tuesday, the result of further testing at a New York City school. Other U.S. cases have been reported in Ohio, Kansas, Texas and California. The U.S. also ordered stepped up border checks in neighboring states.
No one has died outside Mexico but cases have also been confirmed in Canada and Scotland, prompting the World Health Organization on Monday to raise its alert level for the outbreak.
The WHO lifted its pandemic alert to phase 4, meaning there is sustained human-to-human transmission of the virus causing outbreaks in at least one country. It also indicates the risk of a deadly global outbreak.
A 51-year-old South Korean woman also tested positive for swine flu Tuesday after traveling to Mexico but officials said final tests were still necessary. All 315 others on the same flight from Los Angeles were being tested but none have turned up positive, officials said.
In Asia, financial markets were on edge over the risk the flu could develop into a pandemic and kill off fragile signs of recovery in the global economy.
Mexico, where the number of deaths believed caused by swine flu rose by 50 percent on Monday to 152, is suspected to be ground zero of the outbreak.
But Mexican Health Secretary Jose Angel Cordova late Monday said no one knows where the outbreak began, and implied it may have started in the U.S.
"I think it is very risky to say, or want to say, what the point of origin or dissemination of it is, given that there had already been cases reported in southern California and Texas," Cordova told a press conference.
Travel alertsGovernments around the world have taken steps to tighten monitoring of their airports or advised against non-essential travel to Mexico.
Britain, France and Germany issued travel alerts for Mexico. Japan advised its citizens in Mexico to consider returning home soon, saying they might find themselves unable to leave and not be able to get adequate medical care.
The swine flu bug is curable if treated quickly with antiviral medicine but no one is naturally immune.
The virus poses a potentially grave new threat to the U.S. economy, which was showing tentative early signs of a recovery. A widespread outbreak could batter tourism, food and transportation industries, deepening the recession in the U.S. and possibly worldwide.
Putting an alert at phases 4 or 5 signals that the virus is becoming increasingly adept at spreading among humans. That move could lead governments to set trade, travel and other restrictions aimed at limiting its spread.
Phase 6 is for a full-blown pandemic, characterized by outbreaks in at least two regions of the world.
The last pandemic, a Hong Kong flu outbreak in 1968, killed about one million people around the world.
Swine flu
What is it?
Swine influenza is a respiratory disease of pigs first isolated in swine in 1930, according to the Centers for Disease Control and Prevention. The illness is caused by four different type A influenza strains that can cause outbreaks in pigs, though subtypes H1N1 and H3N2 seem to be more common. The death rate among pigs is low, with most infections occurring in the late fall and winter.
Symptoms of infected pigs include fever, depression, coughing (barking), sneezing, difficulty breathing, red or inflamed eyes, lack of appetite and discharge from the nose or eyes.
What are the symptoms?
Symptoms are similar to those of the regular human influenza virus: fever, lethargy, lack of appetite and coughing. Some who have been infected with the swine flu also reported having a runny nose, sore throat, nausea, vomiting and diarrhea

How is it treated?
Four antiviral drugs are licensed to treat the disease in the U.S.: amantadine, rimantadine, oseltamivir and zanamivir. Most of the viruses are susceptible to all four, but the CDC currently recommends oseltamivir or zanamivir to treat and prevent swine flu infections. The antivirals, which are prescription medicines, should be taken as soon as possible symptoms appear.
Tamiflu (the generic name for oseltamivir) and Relenza (the generic name for zanamivir) appear to be effective against the new strain when taken early, says the CDC.
There is currently no human vaccine for swine flu, but the flu vaccine may provide some protection against the H3N2 strain, though not the H1N1 strain.

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